5 New Types of Diabetes

Diabetes has become a little more complicated or clearer, depending on your point of view. According to researchers in Scandinavia, they recommended the classification of diabetes as five types of diseases instead of two types.
But what are these different species and why did the researchers take this decision?
Having diabetes means that a person's blood sugar (glucose) levels are too high. It is an increasingly common disease; About 30 million people in the US have diabetes according to Centers for Disease Control and Prevention. In people with type 1 diabetes, most commonly seen in childhood, a hormone has been discovered that helps the body enter insulin-inducing glucose into the cells. This occurs because the body's immune system attacks the cells in the pancreas that make insulin.
Type 2 diabetes does not make or use insulin well. Most often, this begins with insulin resistance, so even if the body is still hormone, the cells do not respond to insulin. The condition is usually seen in middle-aged or older adults and is thought to be associated with lifestyle factors and obesity.
In a recent study published in The Lancet Diabetes & Endocrinologyl, the researchers found that patients in Sweden and Finland fell into five clusters. One of the clusters was type 1 diabetes, while the other four clusters were type 2 subtypes. Three of the clusters were considered to be severe forms of the disease, while two clusters were accepted as mild forms.

He is an endocrinologist at the Wexner Medical Center at Ohio State University, which is not included in the study. Kathleen Wyne emphasized that the new classification may be very useful, but the researchers do not recommend the release of type 1 and type, and on the contrary, they suggest that there are subtypes.
Iyor This does not change the terminology for diagnosis or diagnosis, Wy said Wyne. He stated that he provides a way to classify ti type 1 and type 2 için in the diagnosis.
The clusters were:


Cluster 1: This form, called diy severe autoimmune diabetes:, is similar to type 1 diabetes. When people in this cluster were diagnosed, they were relatively young and not overweight. He had an immune system (autoimmune) disease that prevented them from producing insulin.
Cluster 2: This form, called ’severe insulin deficiency diabetes,“ resembled cluster 1. People were relatively young at the time of diagnosis and were not overweight. They also didn't produce much insulin. However, most importantly, the immune system was not the cause of diseases. People in this cluster called lar the whole world as type 1 or diabetes, but said they did not have ’autoantibodies’ indicating type 1. The researchers are not sure why this is, but people in this group may have a deficiency in insulin-producing cells.
Cluster 3: This form, termed iler severe insulin resistant diabetes iddet, occurred in people who had overweight and insulin resistance, meaning that their body formed insulin but did not respond to it.
Cluster 4: This form, called eğilim diabetes related to mild obesity “, occurred in people with a milder form of diseases, who had no metabolic problems as in cluster 3, and who tended to be obese.
Cluster 5: This form, called daha mild age-related diabetes bu, was similar to cluster 4, but people were older at the age of diagnosis. This was the most common form of diabetes affecting about 40 percent of people in the study.
People in cluster 3 have the highest risk of kidney disease, a complication of diabetes, while people in cluster 2 can cause the highest risk of retinopathy, and another complication of diabetes can cause vision loss.
The researchers noted that groups 2 and 3 are severe forms of diabetes 2 masked in type 2 diabetes Araştırma. The authors said people in these clusters could benefit from another treatment to prevent diabetes complications.
Improved diagnostics
According to Wyne Live Science, as the article points out, recognizing diabetes subtypes can change how doctors prescribe medications for diabetes.

Ir At the moment, the algorithm used to treat type 2 diabetes is almost all-one-dimensional, Wy said Wyne. Patients usually start a drug called metformin and if it does not work, other drugs are added. However, recognition of subtypes could help doctors choose the first, second or third drug for their patients. The researchers stated that their work had different causes of five diabetes clusters, or that people's classification could not be confirmed over time, so future studies should look at these questions. Researchers also noted that future research can be further enhanced by using other measures, such as genetic markers or blood pressure measurements, in clusters.
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